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Xiaoyan Bai/Deputy Director

Specialties:Renal pathology


Clinical Interests:Diabetic nephropathy


Bio:

2018/12-2020/12"Group-type" Special Support Project for Education Talents in Universities

Vice president,Second Clinical Medical College of Guangdong Medical University

Vice president,Graduate School of Guangdong Medical University

2009/05-2011/05, postdoctoral, Southwest Medical Center, USA


Education:

2003/09-2006/07,Southern Medical University

Department of Pathology, doctor

2000/09-2003/07, Inner Mongolia Medical University

Department of Pathology, master

1994/09-1999/07, Inner Mongolia Medical University

Department of clinical medicine,bachelor


Awards and Honors:

First prize of science and technology award

of Guangdong Province, 2013

Project No. B14-0-1-02-r07


Professional memberships:

Vice chairman of the 9th Youth Committee of Guangdong society of Nephrology

Member of the 10th Youth Committee of Guangdong society of Nephrology

Member of the 4th Youth Committee of Nephrology branch of Chinese Medical Association

Member of the first kidney disease medication Expert Committee of Guangdong Pharmaceutical Association

Member of clinical trial Academic Committee


Publications:

1.Li X , Zhang T, Geng J, Wu ZG, Xu LT, Liu JX, Tian J, Zhou ZM, Nie J, Bai XY*. Advanced Oxidation Protein Products Promote Lipotoxicity and Tubulointerstitial Fibrosis via CD36/β-Catenin Pathway in Diabetic Nephropathy. Antioxid Redox Signal. 2019 Sep 1; 31(7):521-538.

2.Li X , Xu L, Hou X, Geng J, Tian J, Liu X, Bai XY*. Advanced oxidation protein products aggravate tubulointerstitial fibrosis through PKC-dependent mitochondrial injury in early diabetic nephropathy. Antioxid Redox Signal. 2019 Mar 20; 30(9):1162-1185.

3.Diaz IH, Pan JQ, Ricciardi CA, Bai XY, Ke JT, White KE, Flaquer M, Fouli GE, Argunhan F, Hayward AE, Hou FF, Mann GE, Miao RQ, Long DA, Gnudi L. Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature. Diabetes. 2019 Sep; 68(9):1841-1852.

4.Bai XY*, Geng J, Li X, Wan J, Liu J, Zhou ZM, Liu X. Long non-coding RNA LINC01619 regulates miR-27a/FOXO1 and endoplasmic reticulum stress-mediated podocyte injury in diabetic nephropathy. Antioxid Redox Signal. 2018 Feb 17; 118:71-84.

5.Bai XY*, Li X, Tian J, Xu L, Wan J, Liu Y. A new model of diabetic nephropathy in C57BL/6 mice challenged with advanced oxidation protein products. Free Radic Biol Med. 2018 Apr; 118:71-84.

6.Wan J, Hou X, Zhou Z, Geng J, Tian J, Bai XY*, Nie J. WT1 ameliorates podocyte injury via repression of EZH2/β-catenin pathway in diabetic nephropathy. Free Radic Biol Med. 2017 Jul; 108:280-299. doi: 10.1016/j.freeradbiomed.2017.03.012. Epub 2017 Mar 16. (主通讯作者, 2区IF 5.606 )

7.Zhou Z, Wan J, Hou X, Geng J, Li X, Bai XY*. MicroRNA-27a promotes podocyte injury via PPARγ-mediated β-catenin activation in diabetic nephropathy. Cell Death Dis. 2017 Mar 9; 8(3):e2658. doi: 10.1038/cddis.2017.74. (通讯作者, 2区IF 5.965 )

8.Hou XY, Tian JW, Geng J, Li X, Tang X, Zhang J, Bai XY*. MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy. Oncotarget. 2016 Jun 24. doi: 10.18632/oncotarget.10283. [Epub ahead of print]. (通讯作者,JCR1, IF 6.359)

9.Bai XY*, Hou XY, Tian JW, Geng J, Li X. CDK5 Promotes Renal Tubulointerstitial Fibrosis in Diabetic Nephropathy via ERK1/2/PPARγ Pathway. Oncotarget. 2016 Apr 27. doi: 10.18632/oncotarget.9058. [Epub ahead of print] (通讯/第一作者,JCR1, IF 6.359)

10.Bai XY*, Geng J, Zhou ZM, Tian JW, Li X. MicroRNA-130b/PPARγ signaling promotes renal tubulointerstitial fibrosis via activating VEGF-A/TGF-β/SNAIL pathway in diabetic nephropathy. Sci Rep. 2016 Feb 3;6:20475. doi: 10.1038/srep20475. (通讯/第一作者,JCR2, IF 5.578)

11.Bai XY*, Li X, Tian J, Zhou Z. Antiangiogenic treatment diminishes renal injury and dysfunction via regulation of local AKT in early experimental diabetes. PLoS One. 2014 Apr 23; 9(4):e96117. (通讯/第一作者,IF 3.730)

12.Bai XY*, Geng J, Li X, Yang F, Tian J. VEGF-A Inhibition Ameliorates Podocyte Apoptosis via Repression of Activating Protein 1 in Diabetes. Am J Nephrol. 2014; 40:523-534. (通讯/第一作者,IF 2.646)

13.Bai XY, Wu CL. Renal Cell Cancer and Mimics: Pathologic Primer for Radiologists. AJR Am J Roentgenol. 2012 Jun; 198(6):1289-93. (第一作者,IF 2.744)

14.Bai XY, Li X, Wan L, Wang G, Jia N, Geng J. Intravascular large B-cell lymphoma of the kidney: a case report. Diagnostic Pathology. 2011 Sep 23; 6: 86. (第一作者,IF 2.411)

15.Bai XY, Basgen JM. Podocyte number in the maturing rat kidney. Am J Nephrol. 2011; 33(1): 91-6. doi: 10.1159/000322701. Epub 2010 Dec 22. (第一作者,IF 2.646)